No evidence has been put forward that substantiates the claim that SARS-CoV-2 originated in a lab.
2 US government agencies (FBI & DOE) have determined with low or medium confidence that SARS-CoV-2 originated in a lab, but have not revealed their basis for these conclusions.
4 US intelligence agencies lean toward a natural origin for the virus. (source)
Significant evidence (including some published or revealed after the FBI/DOE conclusions were revealed) give compelling reason to believe that a natural origin is far more likely.
The FBI concluded with "moderate confidence" in 2001 that a lab incident was the likely origin of SARS-CoV-2. The FBI has not revealed the basis for this conclusion.
Sources:
https://www.npr.org/2023/02/28/1160214557/fbi-covid-origins-investigation-wray (2023-02-28)
The US Department of Energy has concluded with "low confidence" that SARS-CoV-2 may have originated in a lab leak incident. The basis for this conclusion has not been revealed.
Sources:
https://www.wsj.com/articles/covid-origin-china-lab-leak-807b7b0a (2023-02-06)
"The Huanan Seafood Wholesale Market in Wuhan was the early epicenter of the COVID-19 pandemic"
https://www.science.org/doi/10.1126/science.abp8715 (2022-07-26)
An analysis of samples taken from the Huanan Seafood Wholesale Market in Wuhan show that large amounts of the virus were mixed in with genetic material from racoon dogs.
Article: https://www.nature.com/articles/d41586-023-00998-y (2023-04-05)
Study: https://www.nature.com/articles/s41586-023-06043-2 (2023-04-05)
It took years to find the origin of HIV in chimpanzees.
It took years to trace the path of SARS-CoV(-1) from bat to civet cat to human.
The origin of Ebola is not known.